Role of Flexibility in Protein-DNA-Drug Recognition: The Case of Asp677Gly-Val703Ile Topoisomerase Mutant Hypersensitive to Camptothecin
Figure 6
Atomic distance as a function of time between Lys532Nξ : Tyr723Oδ (a) and Lys532Nξ : Ade11O5′ (b). Both distances have been mediated every 50 frames. The black line and red traces represent the native protein and mutant protein data, respectively.
