Elucidation of the Rotavirus NSP4-Caveolin-1 and -Cholesterol Interactions Using Synthetic Peptides

Figure 8

CD spectra of NSP4_112-140-Cav-1 peptide-peptide interactions in the presence of 1 mM SUV (55 : 35 : 10, POPC/cholesterol/DOPS) in aqueous buffer. (a) NSP4_112-140 + N-Cav_2-20; (b) NSP4_112-140 + Cav_19-40; (c) NSP4_112-140 + Cav_68-80; (d) NSP4_112-140 + C-Cav_161-178. (●) NSP4_112-140 spectra; (∘) Cav-1 peptide spectra; (▼) Theoretical spectra; (Δ)-Observed spectra.

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