Review Article
Glutathione Homeostasis and Functions: Potential Targets for
Medical Interventions
Table 1
Phytochemicals that are known to activate the Nrf2/Keap1 signalling pathway in human and animal systems with identified mechanisms.
|
Phytochemical | Keap1 | Nrf2 |
References | | Oxidation | Alkylation | Ubiquitination | Phosphorylation | |
| Sulforaphane | − | + | ? | ? | [199, 200] | Curcumin | + | − | − | ? | [201] | Epigallocatechin gallate | | | | + | [202] | Allyl sulfides | ? | | | + | [203, 204] | Resveratrol | | | | + | [205] | Capsaicin | | | | + | [206] | -Shogaol | | + | | | [207] | Lycopene | | | | | [208] | Carnosol | | | | + | [209] | Xanthohumol | | + | | | [210] |
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