Amino Acid Derivatives as New Zinc Binding Groups for the Design of Selective Matrix Metalloproteinase Inhibitors
Figure 3
Docked poses of 1a (a) and 1e in both enantiomeric forms (b) into the MMP-2 active site. MMP-2 is represented as a grey cartoon. Ligands and most relevant residues are depicted as sticks. H-bonds are represented as green dashed lines.