Amino Acid Derivatives as New Zinc Binding Groups for the Design of Selective Matrix Metalloproteinase Inhibitors
Figure 4
Docked poses of 25a into the MMP-2 active site (a) and 25d into MMP-8 active site (b). MMP-2 and MMP-8 are represented, respectively, as a grey and dark grey cartoons. Ligands and most relevant residues are depicted as sticks. H-bonds are represented as green dashed lines.
