Research Article

Ischemia Induces Release of Endogenous Amino Acids from the Cerebral Cortex and Cerebellum of Developing and Adult Mice

Figure 1

Time course of basal (- -) and K+-evoked (- -) GABA release from cerebral cortical slices in normoxia and basal (-∆-) and K+-stimulated (-▴-) GABA release in ischemia in 7-day-old (a) and 3-month-old (b) mice. The results are means of 4–8 independent experiments with SEMs indicated. Ischemia significantly ( ) enhanced the release at both ages. K+ stimulation was likewise significantly effective. Note the threefold difference in the scale of the -axis in panels (a) and (b).
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(a)
839036.fig.001b
(b)