Development of a Novel Cysteine Sulfinic Acid Decarboxylase Knockout Mouse: Dietary Taurine Reduces Neonatal Mortality

Table 6

Fold change of taurine-related genes in G3 HO and G3 HOT compared to WT.

Gene	Genotype	Liver	Brain
Csad	WT	1.0±0.03^1	ND^2
	G3 HO	<0.002**
	G3 HOT	<0.001**
Cdo	WT	1.0±0.05	1.0±0.03
	G3 HO	1.3±0.10^∗	1.1±0.10
	G3 HOT	1.1±0.09	1.3±0.30
Ado	WT	1.0±0.03	1.0±0.09
	G3 HO	1.1±0.06	1.0±0.10
	G3 HOT	1.3±0.08^∗	1.1±0.20
TauT	WT	1.0±0.06	1.0±0.08
	G3 HO	1.2±0.07	1.4±0.10
	G3 HOT	1.2±0.09	1.3±0.30

¹Data represent mean ± SE from 4 WT, 6 G3 HO, and 4 G3 HOT at PD1, respectively.
²ND means not determined due to low expression in the brain.
*Significantly different compared to WT, 𝑃<0.05.
**Significantly different compared to WT, 𝑃<0.001.