FLUed: A Novel Four-Layer Model for Simulating Epidemic Dynamics and Assessing Intervention Policies
Table 1
FLUed model expert-identified epidemic parameters used for fitting simulation curves with actual 2008-2009 seasonal influenza A and 2009 swine-origin influenza A (H1N1) curves in Taiwan.
Default value
Layer
Attribute
2008-2009 seasonal influenza A
2009 swine-origin influenza A (H1N1)
Description
Source reference
Children
Adults
Seniors
Children
Adults
Seniors
1
1.3333
0.6667
0.6667
2.6667
1.3333
1.3333
Transmission rate from investigated/diagnosed/treated age group p to same-age group in town i.
Huang et al.'s [4], Longini et al.'s [31, 32] and Stroud et al.'s [33] parameter estimates and Expert-based parameter estimation method (EBPEM)
3.3333
1.6667
1.6667
3.3333
1.6667
1.6667
Transmission rate from investigated/misdiagnosed age group p to same-age group in town i.
3.3333
1.6667
1.6667
3.3333
1.6667
1.6667
Transmission rate from noninvestigated age group p to same-age group in town i.
0.0714
0.0714
Latent rate of age group p in town i.
0.1429
0.3333
Removal rate of investigated/diagnosed/treated age group p in town i.
0.2500
0.1429
Removal rate of misdiagnosed age group p in town i.
0.1429
0.1667
Removal rate of non-investigated age group p in town i.
0.6
Investigation ratio (investigated proportion of age group p in town i).
0.6
Detection ratio (correctly diagnosed proportion of age group p in town i).
3.0
Delay time between investigation and correct diagnosis.
2
Target (q)
Target (q)
Transmission rate from investigated/diagnosed/treated age group p to age group q in town i.
Huang et al.'s [4], Longini et al.'s [31, 32] and Stroud et al.'s [33] parameter estimates and expert-based parameter estimation method (EBPEM)
Children
Adults
Seniors
Children
Adults
Seniors
Children
×
0.6667
0.6667
Children
×
1.3333
1.3333
Source (p)
Adults
1.3333
×
0.6667
Source (p)
Adults
2.6667
×
1.3333
Seniors
1.3333
0.6667
×
Seniors
2.6667
1.3333
×
Children
Adults
Seniors
Children
Adults
Seniors
Transmission rate from misdiagnosed age-group p to age group q in town i.
Children
×
1.6667
1.6667
Children
×
1.6667
1.6667
Source (p)
Adults
3.3333
×
1.6667
Source (p)
Adults
3.3333
×
1.6667
Seniors
3.3333
1.6667
×
Seniors
3.3333
1.6667
×
Children
Adults
Seniors
Children
Adults
Seniors
Transmission rate from the non-investigated age group p to age group q in town i.
Children
×
1.6667
1.6667
Children
×
1.6667
1.6667
Source (p)
Adults
3.3333
×
1.6667
Source (p)
Adults
3.3333
×
1.6667
Seniors
3.3333
1.6667
×
Seniors
3.3333
1.6667
×
Age group p as a percentage of town i population.
Census database of Republic of China (ROC) Interior Ministry
3
Adults
Binary value for commuter age group.
Transportation and census databases of ROC Transportation Institute
Population of town i as a percentage of the largest town’s population.
Commuting weight (number of commuters from town i to town j).
4
0.8
Intercity rate (average number of daily contacts among individuals in location i).
