Research Article

Adding Education to “Test and Treat”: Can We Overcome Drug Resistance?

Table 1

Parameter definitions.

Variable Definition Sample value Range UnitsReference

Susceptible population at time (state variable) People

Infected population at time who do not know their status (state variable) People

Uneducated infected population at time who know their status (state variable) People

Infected, educated population at time who know their status (state variable) People

Infected, uneducated, and treated population at time (state variable) People

Infected, educated, and treated population at time (state variable) People

Infected, uneducated, and drug-resistant population at time (state variable) People

Infected, educated, and drug-resistant population at time (state variable) People

Recruitment rate 29 25–35Year[34]

Transmission rate 0.05–0.95 Year[34]

Rate of knowing one's status 0.550.1–1 YearAssumed

The proportion of HIV-positive individuals who are educated immediately upon knowing their status0.750-1Assumed

The rate of providing treatment for uneducated people0.11250.1–4 Year[34]

The rate of providing treatment for educated people 0.11250.1–4 YearAssumed

The rate at which uneducated people become drug resistant Year Assumed

The rate at which educated people become drug resistant Year Assumed

Modifying transmission parameter for uneducated people 1.685 1–2.37 [9]

Modifying transmission parameter for educated people0.3430.186–1 [9]

Modifying transmission parameter for uneducated and treated people 0.180.174–0.186[9]

Modifying transmission parameter for educated and treated people 0.0920.01–0.174[9]

The rate at which uneducated people stop their treatment0.1250.1–0.15 YearAssumed

The rate at which educated people stop their treatment 0.05050.1–0.15 YearAssumed

The rate of providing late education for nontreated HIV-positive individuals 10–2 YearAssumed

The rate of providing late education during or after treatment10–2 YearAssumed

Natural mortality rate 0.02 0.015–0.025 Year[34]

Rate of progression to AIDS for nontreated or drug-resistant individuals 0.1 0.05–0.15 Year[34]

Rate of progression to AIDS for treated individuals0.08750.05–0.125 YearAssumed