Research Article

Simultaneous Analysis of Losartan Potassium, Amlodipine Besylate, and Hydrochlorothiazide in Bulk and in Tablets by High-Performance Thin Layer Chromatography with UV-Absorption Densitometry

Figure 1

Typical densitogram obtained from losartan potassium ( 𝑅 𝐹 = 0 . 7 4 ), amlodipine besylate ( 𝑅 𝐹 = 0 . 3 5 ), and hydrochlorothiazide ( 𝑅 𝐹 = 0 . 5 7 ). Detection was at 254 nm and the mobile phase was chloroform : methanol : acetone : formic acid 7.5 : 1.3 : 0.5 : 0.03 ( 𝑣 / 𝑣 / 𝑣 / 𝑣 ).
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