Detection of Quadruplex DNA by Gold Nanoparticles

Table 1

Percent change (±4%) in gold nanoparticle PRLS signal, in presence of preannealed and annealed DNA, and when samples were annealed in the presence of nanoparticles. DNA concentration is 2.1 nM in each case.

DNA	Preannealed	Annealed in presence of AuNPs	Annealed DNA added to AuNPs
15 mer, no K^+	0	31	29
15 mer, K^+	26	85	87
Triplet, (GGC)3	18	100	95
12 mer	0	63	61