A Sensitive and Selective Method for Determination of Aesculin in Cortex Fraxini by Liquid Chromatography Quadrupole Time-of-Flight Tandem Mass Spectrometry and Application in Pharmacokinetic Study

<table>Representative extracted chromatograms for (a) blank plasma, (b) blank plasma containing 40.0 ng/mL aesculin and 10.0 ng/mL IS, (c) blank plasma containing 500.0 ng/mL aesculin and 10.0 ng/mL IS, (d) blank plasma containing 1200.0 ng/mL aesculin and 10.0 ng/mL IS, and (e) plasma sample collected at 0.17 after single oral dose of Cortex fraxini extract (5.0 mL/kg).</table>

Journal of Analytical Methods in Chemistry

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Figure 1

Figure 1: A Sensitive and Selective Method for Determination of Aesculin in Cortex Fraxini by Liquid Chromatography Quadrupole Time-of-Flight Tandem Mass Spectrometry and Application in Pharmacokinetic Study 

Figure 1 | A Sensitive and Selective Method for Determination of Aesculin in Cortex Fraxini by Liquid Chromatography Quadrupole Time-of-Flight Tandem Mass Spectrometry and Application in Pharmacokinetic Study 