Research Article

Optimization of IC Separation Based on Isocratic-to-Gradient Retention Modeling in Combination with Sequential Searching or Evolutionary Algorithm

Figure 3

Searching for the appropriate number of simplex factors ( ) and concentration interval ( ). The above chromatograms were obtained for (a) and 3 for all , and , 45, and 90 mM KOH, and and 90 mM KOH, (b) and  mM KOH, (c) and  mM KOH, (d) and  mM KOH, (e) and  mM KOH, (f) and  mM KOH, (g) and  mM KOH, and (h) and  mM KOH.
549729.fig.003a
(a)
549729.fig.003b
(b)
549729.fig.003c
(c)
549729.fig.003d
(d)
549729.fig.003e
(e)
549729.fig.003f
(f)
549729.fig.003g
(g)
549729.fig.003h
(h)