Research Article
Effects of Borneol on Pharmacokinetics and Tissue Distribution of Notoginsenoside R1 and Ginsenosides Rg1 and Re in Panax notoginseng in Rabbits
Table 3
Stability of of NGR1, GRg1, and GRe in plasma samples and tissue homogenates of rabbits (
).
| Biosample | QC conc (μg · mL−1) | Remaining (mean ± S.D.) | Short-term stability | Long-term stability | Freeze-thaw stability |
| NGR1 | | | | | | 0.5 | | | | Plasma | 5.0 | | | | | 35.0 | | | | | 0.5 | | | | Heart | 5.0 | | | | | 50.0 | | | | | 0.5 | | | | Liver | 5.0 | | | | | 50.0 | | | | | 0.5 | | | | Brain | 5.0 | | | | | 50.0 | | | | | 0.5 | | | | Lung | 5.0 | | | | | 50.0 | | | | | 0.5 | | | | Kidney | 5.0 | | | | | 50.0 | | | | GRg1 | | | | | | 0.4 | | | | Plasma | 3.0 | | | | | 40.0 | | | | | 0.4 | | | | Heart | 3.0 | | | | | 40.0 | | | | | 0.4 | | | | Liver | 3.0 | | | | | 40.0 | | | | | 0.4 | | | | Brain | 3.0 | | | | | 40.0 | | | | | 0.4 | | | | Lung | 3.0 | | | | | 40.0 | | | | | 0.4 | | | | Kidney | 3.0 | | | | | 40.0 | | | | GRg1 | | | | | | 0.4 | | | | Plasma | 3.0 | | | | | 40.0 | | | | | 0.4 | | | | Heart | 3.0 | | | | | 40.0 | | | | | 0.4 | | | | Liver | 3.0 | | | | | 40.0 | | | | | 0.4 | | | | Brain | 3.0 | | | | | 40.0 | | | | | 0.4 | | | | Lung | 3.0 | | | | | 40.0 | | | | | 0.8 | | | | Kidney | 8.0 | | | | | 48.0 | | | |
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