Validation and Application of a New Reversed Phase HPLC Method for <i>In Vitro</i> Dissolution Studies of Rabeprazole Sodium in Delayed-Release Tablets

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td align="left">Parameters</td><td align="center">Value (mean ± %RSD), <svg height="7.9499998" id="M12" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 8.6625004 7.9499998" width="8.6625004" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,7.675)"><path d="M495 86q-46 -47 -87 -72.5t-63 -25.5q-43 0 -16 107l49 210q7 34 8 50.5t-3 21t-13 4.5q-35 0 -109.5 -72.5t-115.5 -140.5q-21 -75 -38 -159q-50 -10 -76 -21l-6 8l84 340q8 35 -4 35q-17 0 -67 -46l-15 26q44 44 85.5 70.5t64.5 26.5q35 0 10 -103l-24 -98h2
q42 56 97 103.5t96 71.5q46 26 74 26q9 0 16 -2.5t14 -11.5t9.5 -24.5t-1 -44t-13.5 -68.5q-30 -117 -47 -200q-4 -19 -3.5 -25t6.5 -6q21 0 70 48z" id="x1D45B"></path></g>
</svg> = 6</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td align="left">Peak area</td><td align="center">206343 ± 0.2</td></tr><tr><td align="left">Tailing factors</td><td align="center">1.1 ± 1.5</td></tr><tr><td align="left">Retention time (min)</td><td align="center">2.7 ± 0.1</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Chromatographic characteristics of system suitability study.

Journal of Analytical Methods in Chemistry

tab1

Table 1

Table 1: Validation and Application of a New Reversed Phase HPLC Method for <i>In Vitro</i> Dissolution Studies of Rabeprazole Sodium in Delayed-Release Tablets 

Table 1 | Validation and Application of a New Reversed Phase HPLC Method for In Vitro Dissolution Studies of Rabeprazole Sodium in Delayed-Release Tablets 