Validation and Application of a New Reversed Phase HPLC Method for In Vitro Dissolution Studies of Rabeprazole Sodium in Delayed-Release Tablets

Table 3

Accuracy studies of RPS in drug-placebo solutions.

Sample conc. %	Amount added (μg/mL)	Peak area of sample	Amount recovered (μg/mL)	% Recovery	% Recovery; (mean ± %RSD)
0.0	0.0	0.0	0.0	0.0	0.0
	0.0	0.0	0.0	0.0
	0.0	0.0	0.0	0.0
50	5.0	97466	5.1	101.9	101.7 ± 0.4
	5.0	96848	5.0	101.2
	5.0	97472	5.1	101.9
100	10.0	193783	10.1	101.3	101.4 ± 0.2
	10.0	194406	10.1	101.6
	10.0	193829	10.1	101.3
120	12.0	229764	12.0	100.1	100.0 ± 0.1
	12.0	229820	12.0	100.1
	12.0	229235	12.0	99.9