Research Article

Studies on the Anti-Inflammatory Effect and Its Mechanisms of Sophoridine

Table 2

The influences of SRI on carrageenin-induced mouse paw edema model .

GroupDosage (mg/kg)Difference between left and right paw (mg) (mean ± SD)Inhibition (%)

Model0.083 ± 0.211
Ibuprofen176.50.039 ± 0.009(1)53.01
SRI (LD50/5)48.600.057 ± 0.010(1)31.32
SRI (LD50/20)12.150.058 ± 0.019(1)30.12

Compared with model group, (1) .