Single-Round Patterned DNA Library Microarray Aptamer Lead Identification

Figure 1

Microarray performance of the top 15 ranked potential thrombin binders of PT2 compared to controls. Inset: close-up view of the intensities of the top 5 ranked sequences compared to the negative control. Error bars represent standard deviation of replicates of fluorescence values obtained from a 2 h incubation of 100 nM Cy3-thrombin with the microarray at 20°C.