Comparative Pharmacokinetics and Bioavailability of Epimedin C in Rat after Intramuscular Administration of Epimedin C, a Combination of Four Flavonoid Glycosides and Purified Herba Epimedii Extract

Figure 4

Typical MRM chromatograms of epimedin C (1) and IS (2). (a) Blank rat plasma; (b) blank plasma sample spiked with epimedin C at LLOQ and IS (66.7 ng/mL); (c) rat plasma sample at 15 min after intramuscular injection of epimedin C; (d) rat plasma sample at 15 min after intramuscular administration of combination solution of four flavonoid glycosides; (e) rat plasma sample at 15 min after intramuscular administration of CKZ.

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