Anticoagulation for Atrial Fibrillation: Is This the End of Warfarin? Not Just Yet

Table 3

Showing the relative pharmacokinetics of the novel oral anticoagulants.

	Dabigatran	Rivaroxaban	Apixaban
Target	Thrombin	Factor Xa	Factor Xa
Dose	Twice daily	Once daily	Twice daily
Half-life in hours	12–17	5–9 (but effect last for 24 hours)	12
Renal excretion	80%	25%	33%
Hepatic excretion	20%	75%	67%