Striatal Hypodensities, Not White Matter Hypodensities on CT, Are Associated with Late-Onset Depression in Alzheimer's Disease

Table 3

Risk of confluent frontal lobe deep white matter hypodensities in late-onset depression compared with No depression for all dementia and alzheimer’s disease.

	No depression		Late-onset depression
	−Con WMH	+Con WMH	−Con WMH	+Con WMH	OR*
	𝑁 (%)	𝑁 (%)	𝑁 (%)	𝑁 (%)	(95% CI)
All dementia	97 (73.5)	35 (26.5)	23 (63.9)	13 (36.1)	1.58 (0.72, 3.46)
AD only	73 (76.8)	22 (23.2)	16 (64.0)	9 (36.0)	1.83 (0.70, 4.79)

−ConWMH: Confluent frontal deep white matter hypodensities absent; +ConWMH: Confluent frontal deep white matter hypodensities present; OR: Binary logit odds ratio estimate, controlling for gender; CI: confidence interval; AD: Alzheimer’s disease.
*Late-onset depression group compared to no depression group.