Striatal Hypodensities, Not White Matter Hypodensities on CT, Are Associated with Late-Onset Depression in Alzheimer's Disease

Table 4

risk of frontal lobe deep white matter hypodensities in late-onset depression compared with no depression for all dementia and Alzheimer’s disease.

	No depression		Late-onset depression
	−WMH	+WMH	−WMH	+WMH	OR
	𝑁 (%)	𝑁 (%)	𝑁 (%)	𝑁 (%)	(95% CI)*
All dementia	75 (56.8)	57 (43.2)	22 (61.1)	14 (38.9)	0.96 (0.44, 2.08)
AD only	59 (62.1)	36 (37.9)	16 (64.0)	9 (36.0)	0.88 (0.35, 2.25)

−WMH: frontal deep white matter hypodensities absent; +WMH: frontal deep white matter hypodensities present; OR: binary logit odds ratio estimate, controlling for gender; CI: confidence interval; AD: Alzheimer’s disease.
*Late-onset depression group compared to no depression group.