Diffusion Tensor Imaging Evaluation of Corticospinal Tract Hyperintensity in Upper Motor Neuron-Predominant ALS Patients

Table 1

Percent correspondence of abnormal CST DTI metrics with appropriate side of body showing more UMN signs.

	CP		IC		LV		PMC
Body predominance of UMN signs	Left (%)	Right (%)	Left (%)	Right (%)	Left (%)	Right (%)	Left (%)	Right (%)
FA	50	33.00	85	28	68.40	66.60	16.60	45.50
AD (mm^2s^−1)	50	61.1	30	33	73.6	55.5	41.6	36.3
RD (mm^2s^−1)	50	55.5	30	94.4	52.6	55.5	58.3	45.4
MD (mm^2s^−1)	50	55.5	15	94.4	52.6	61.1	58.3	36.3

Key: AD: axial diffusivity, CP: cerebral peduncle, CST: corticospinal tract, FA: fractional anisotropy, IC: posterior limb of internal capsule, LV: centrum semiovale at top of lateral ventricle, MD: mean diffusivity, PMC: subjacent to primary motor cortex, RD: radial diffusivity, UMN: upper motor neuron.