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Journal of Aging Research
Volume 2011 (2011), Article ID 805062, 10 pages
http://dx.doi.org/10.4061/2011/805062
Research Article

Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men

1Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA
2Prevention Research Center, University of South Carolina, Columbia, SC, USA
3Cancer Prevention and Control Program and Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA

Received 26 January 2011; Accepted 9 May 2011

Academic Editor: Leonard W. Poon

Copyright © 2011 Erin K. Howie et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This study examined the association between consumption of alcoholic beverages and all-cause and cardiovascular disease (CVD) mortality in a cohort of men ( 𝑛 = 3 1 ,367). In the Cox proportional hazards model adjusted for age, year of examination, body mass index (BMI), smoking, family history of CVD, and aerobic fitness, there were no significant differences in risk of all-cause mortality across alcohol intake groups. Risk of CVD mortality was reduced 29% in quartile 1 (HR = 0.71, 95% confidence interval (CI): 0.53, 0.95) and 25% in quartile 2 (HR = 0.75, 95% CI: 0.58, 0.98). The amount of alcohol consumed to achieve this risk reduction was <6 drinks/week; less than the amount currently recommended. The addition of other potential confounders and effect modifiers including blood pressure, insulin sensitivity, lipid levels, and psychological variables did not affect the magnitude of association. Future research is needed to validate the current public health recommendations for alcohol consumption.