Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men
Table 2
Hazard ratios of all-cause mortality by alcohol consumption level in men, Aerobics Center for Longitudinal Study (ACLS), 1974–2002.
Alcohol consumption (drinks/week)
Nondrinkers (0)
Quartile 1 (1–3)
Quartile 2 (4–6)
Quartile 3 (7–13)
Quartile 4 (≥14)
Person-years
86,872
91,529
98,303
103,625
124,360
No.
4870
6733
6150
6841
7043
No. of Deaths
343
237
350
349
555
Death ratea
43.8
37.2
43.3
41.6
51.2
Basic modelb
1.00 (referent)
0.86 (0.73–1.01)
0.95 (0.82–1.10)
0.97 (0.83–1.12)
1.09 (0.95–1.25)
Basic model plus
Blood pressure factorsc
1.00 (referent)
0.86 (0.73–1.02)
0.94 (0.81–1.09)
0.97 (0.83–1.12)
1.06 (0.92–1.21)
Fasting glucose factorsd
1.00 (referent)
0.84 (0.71–0.99)
0.95 (0.82–1.10)
0.96 (0.82–1.11)
1.07 (0.94–1.23)
Lipid factorse
1.00 (referent)
0.86 (0.73–1.01)
0.95 (0.82–1.11)
0.96 (0.83–1.12)
1.09 (0.95–1.25)
All intermediate factorscde
1.00 (referent)
0.84 (0.71–0.99)
0.94 (0.81–1.09)
0.96 (0.82–1.11)
1.05 (0.91–1.20)
aDeath rate per 10,000 person-years adjusted for age (in years).
bAdjusted for age (in years), year of examination, BMI (kg/m2), smoking (current smoker or not), family history of CVD (yes or no), and maximal treadmill time (min).
cSystolic blood pressure and reported hypertension (yes or no).
dFasting glucose and reported diabetes (yes or no).
eTotal cholesterol and triglyceride.