Table 3: Hazard ratios of CVD mortality by alcohol consumption level in men, Aerobics Center for Longitudinal Study (ACLS), 1974–2002.

Alcohol consumption (drinks/week)
Nondrinkers (0)Quartile 1 (1–3)Quartile 2 (4–6)Quartile 3 (7–13)Quartile 4 (≥14)

Person-years86,87291,52998,303103,625124,360
No.47426663604967356860
No. of Deaths12870101106183
Death ratea17.011.613.112.917.7
Basic modelb1.00 (referent)0.71 (0.530.95)0.75 (0.580.98)0.83 (0.64–1.08)1.00 (0.80–1.26)
Basic model plus
 Blood pressure factorsc1.00 (referent)0.70 (0.530.94)0.73 (0.560.95)0.84 (0.64–1.09)0.94 (0.75–1.18)
 Fasting glucose factorsd1.00 (referent)0.68 (0.510.91)0.75 (0.580.98)0.82 (0.63–1.07)0.98 (0.78–1.24)
 Lipid factorse1.00 (referent)0.71 (0.530.95)0.73 (0.560.96)0.80 (0.62–1.04)0.95 (0.75–1.19)
 All intermediate factorscde1.00 (referent)0.68 (0.510.91)0.71 (0.550.93)0.81 (0.62–1.05)0.88 (0.69–1.11)

aDeath rate per 10,000 person-years adjusted for age (in years).
bAdjusted for age (in years), year of examination, BMI (kg/m2), smoking (current smoker or not), family history of CVD (yes or no), and maximal treadmill time (min).
cSystolic blood pressure and reported hypertension (yes or no).
dFasting glucose and reported diabetes (yes or no).
eTotal cholesterol and triglyceride.