Research Article

Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men

Table 4

Hazard ratios of all-cause mortality stratified by risk factorsa, Aerobics Center for Longitudinal Study (ACLS), 1974–2002.

Alcohol consumption (drinks/week)
Nondrinkers (0)Quartile 1 (1–3)Quartile 2 (4–6)Quartile 3 (7–13)Quartile 4 (≥14)

Age
 Age <60 1.00 (referent)0.80 (0.660.96)0.92 (0.78–1.09)1.02 (0.86–1.20)1.08 (0.93–1.26)
 Age ≥60 1.00 (referent)0.86 (0.59–1.25)0.85 (0.59–1.23)0.75 (0.52–1.08)1.04 (0.76–1.44)
BMI
 BMI <25 1.00 (referent)0.85 (0.65–1.11)1.03 (0.80–1.32)0.95 (0.74–1.22)0.97 (0.77–1.23)
 BMI ≥25 1.00 (referent)0.86 (0.70–1.06)0.90 (0.75–1.09)0.96 (0.79–1.16)1.12 (0.95–1.33)
Health statusb
 Healthy 1.00 (referent)0.91 (0.69–1.20)0.92 (0.71–1.19)1.10 (0.86–1.42)1.11 (0.87–1.41)
 Unhealthy 1.00 (referent)0.82 (0.67–1.01)0.97 (0.81–1.17)0.88 (0.73–1.07)1.05 (0.89–1.24)
Fitness level
 Unfit (least fit 20%) 1.00 (referent)0.91 (0.67–1.22)1.02 (0.79–1.32)1.10 (0.83–1.44)1.17 (0.92–1.48)
 Fit (most fit 80%) 1.00 (referent)0.84 (0.69–1.03)0.91 (0.76–1.10)0.87 (0.73–1.05)1.01 (0.85–1.19)

aAdjusted for year of examination, smoking (current smoker or not), family history of CVD (yes or no), and each other factor in the table.
bDefined as presence or absence of one or more of following diseases: hypertension, diabetes, or hyperlipidemia.