Table 2: Prostaglandin-related pharmacological agents in the treatment of cardiovascular diseases.

ModulatorDrugs (trade name)Clinical applicationReferences

PGI2 and its stable analoguesEpoprostenol sodium (Flolan), Beraprost sodium (Procyclin), Iloprost (Ventavis), Treprostinil (Remodulin)Primary pulmonary hypertension, pulmonary arterial hypertension[200207]
PGE2 and its analoguesDinoprostone, ViprostolCongenital heart disease[208210, 214217]
TXS inhibitorsDazoxiben, Camonagrel, Picotamide (Dusodril)Thrombosis, atherosclerosis, arrhythmias[218226]
TP inhibitorsPicotamide, S18886 (Triplion)Thrombosis, atherosclerosis, ischemic stroke, myocardial infarction[84, 223227]
COX1 inhibitorAspirinThrombosis, atherosclerosis, ischemic stroke, myocardial infarction[231235]