Research Article

Association of Social Engagement with Brain Volumes Assessed by Structural MRI

Table 1

Descriptive statistics.

  𝑁 (%)Social Engagement
(Range βˆ’0.79, 1.09)
(SD)Total brain volume
(Range 880.6, 1449.3)
(SD)

All348(100%)0.01(0.33)1137.4(100.4)
Age      
 48–5982(23.6%)βˆ’0.07(0.35)1187.5(94.6)
  60–6492(26.4%)0.04(0.32)1161.3(90.6)
 65–6984(24.1%)0.02(0.29)1123.9(81.8)
 70–8290(25.9%)0.07(0.33)1079.7(100.4)
    𝑃 = 0 . 0 2 8   𝑃 < 0 . 0 0 1  
Race/ethnicity      
 White/Non-Hispanic315(90.5%)0.02(0.32)1141.6(99.9)
 All other33(9.6%)βˆ’0.05(0.40)1097.1(97.9)
    𝑃 = 0 . 2 5   𝑃 = 0 . 0 1 5  
Educational attainment      
 <High school25(7.2%) βˆ’0.05 (0.41)1083.1(74.7)
 High school90(25.9%) βˆ’0.05 (0.32)1139.8(97.4)
 High school + trade school167(48.0%)0.03(0.30)1135.8(101.6)
 College degree56(16.1%)0.04(0.34)1171.6(92.2)
 Graduate degree10(2.9%)0.28(0.41)1086.1(137.9)
    𝑃 = 0 . 0 1 8   𝑃 = 0 . 0 0 2  
Hypertension      
 Yes180(51.7%)0.01(0.32)1116.6(97.5)
 No168(48.3%)0.01(0.33)1159.6(99.0)
    𝑃 = 0 . 9 7   𝑃 < 0 . 0 0 1  
Diabetes      
 Yes54(15.5%)βˆ’0.01(0.29)1098.8(90.5)
 No294(84.5%)0.02(0.34)1144.4(100.7)
    𝑃 = 0 . 5 9   𝑃 = 0 . 0 0 2  
Control status      
 Population-based control43(12.4%)0.12(0.29)1103.5(100.5)
 Former lead worker305(87.6%)0.00(0.33)1142.1(99.6)
    𝑃 = 0 . 0 1 8   𝑃 = 0 . 0 1 8  

All 𝑃 -values from analysis of variance (ANOVA) tests.