Elevated Serum Carboxymethyl-Lysine, an Advanced Glycation End Product, Predicts Severe Walking Disability in Older Women: The Women's Health and Aging Study I

Table 3

Multivariate cox proportional hazard models for serum CML and development of severe walking disability, (𝑁=394)¹.

Scenario	H.R.^2	95% C.I.	𝑃
(1) All women with missing data had multiple simulations to impute severe walking disability status prior  to death.	1.63	1.06, 2.49	0.03
(2) Inverse probability weighting method (IPW)	1.56	1.04, 2.36	0.03
(3) All women with missing data treated as censored, that is, no severe walking disability prior to death.	1.46	0.95, 2.23	0.08
(4) All women with missing data treated as developing severe walking disability prior to death.	1.54	1.04, 2.29	0.03

¹All models adjusted for age, congestive heart failure, peripheral artery disease, diabetes mellitus, and renal insufficiency.
²Highest quartile of serum CML versus lower three quartiles.