Blockade of Electron Transport at the Onset of Reperfusion Decreases Cardiac Injury in Aged Hearts by Protecting the Inner Mitochondrial Membrane

<table>Time course of ischemia and reperfusion. In the untreated rat heart group after 25 min global ischemia, the heart underwent 30 min reperfusion. In the amobarbital- (AMO-) treated group, the drug (2.5 mM) was given for three min at the onset of reperfusion followed by 27 min of untreated Krebs-Henseleit buffer perfusion (upper panel). In isolated mouse hearts, hearts were subjected to 30 min global ischemia and 60 min reperfusion with and without amobarbital treatment. The infarct size was determined at the end of reperfusion (lower panel).</table>

Journal of Aging Research

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Figure 1

Figure 1: Blockade of Electron Transport at the Onset of Reperfusion Decreases Cardiac Injury in Aged Hearts by Protecting the Inner Mitochondrial Membrane 

Figure 1 | Blockade of Electron Transport at the Onset of Reperfusion Decreases Cardiac Injury in Aged Hearts by Protecting the Inner Mitochondrial Membrane 