Blockade of Electron Transport at the Onset of Reperfusion Decreases Cardiac Injury in Aged Hearts by Protecting the Inner Mitochondrial Membrane

Figure 5

Mitochondrial inner membrane potential following ischemia-reperfusion. Amobarbital treatment during reperfusion improved inner mitochondrial potential measured following 30 minutes of reperfusion in both SSM (a) and IFM (b) in the presence of ADP (ψ 1), oligomycin (ψ 2), and DNP (ψ 3). ψ 1–3 conditions are as shown in Figure 4. (Mean ± SEM; *𝑃<0.05 versus untreated 𝑛=10 in each group.)

(a)

(b)