Research Article

Blockade of Electron Transport at the Onset of Reperfusion Decreases Cardiac Injury in Aged Hearts by Protecting the Inner Mitochondrial Membrane

Table 1

Oxidative phosphorylation in SSM and IFM following ischemia-reperfusion.

SSMIFM
ISC-REPAMO + REPISC-REPAMO + REP

Glutamate-ADP 9 4 ± 1 0 1 0 9 ± 1 1 1 2 3 ± 1 1 1 4 5 ± 1 4
Glutamate-DNP 9 3 ± 9 1 1 4 ± 1 3 1 2 1 ± 1 2 1 4 9 ± 1 5
Succinate-ADP 1 0 0 ± 9 1 2 4 ± 1 0 1 2 7 ± 1 0 1 5 4 ± 1 3
Succinate-DNP 9 7 ± 9 1 1 9 ± 1 0 1 2 1 ± 1 0 1 4 8 ± 1 3
TMPD-ADP 4 0 8 ± 2 3 4 3 8 ± 1 6 4 8 8 ± 2 8 5 6 0 ± 3 6

Data are expressed as mean ± SEM; P = NS, ISC-REP versus AMO + REP, 𝑁 = 1 0 in each group.