Clinical Study
Could Some Geriatric Characteristics Hinder the Prescription of Anticoagulants in Atrial Fibrillation in the Elderly?
Table 2
Comparison of patients with AF according to their anticoagulation status.
(a) Geriatric characteristics |
| | Not anticoagulated | Anticoagulated | | | Mean (SD) or % | | Mean (SD) or % |
| Institution (long term care) | 56 | 37.5% | 84 | 26.2% | 0.155 | Number of classes of drugs | 54 | 6.5 (2.9) | 86 | 8.2 (3.2) | 0.001 | Drug management ability | 53 | 51% | 80 | 50% | 0.915 | ISAR (points) | 56 | 3.4 (1.7) | 86 | 3.5 (1.6) | 0.6173 | % ISAR ≥ 1 | 56 | 95% | 86 | 98% | 0.338 | % ISAR ≥ 2 | 56 | 82% | 86 | 85% | 0.665 | GDS (points) | 56 | 0.9 (1.4) | 86 | 0.8 (1.4) | 0.619 | % GDS > 1 | 56 | 38% | 86 | 30% | 0.368 | % patients who fell < 6 months | 50 | 30% | 77 | 36% | 0.459 | % weight loss | 53 | 36% | 78 | 32% | 0.651 | % albumin < 3.5 g/100 mL | 47 | 26% | 69 | 25% | 0.913 |
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(b) Comorbidities |
| | Not anticoagulated | Anticoagulated | | | % | | % |
| % hospitalized < 6 months | 52 | 33% | 83 | 52% | 0.030 | Charlson (points) | 54 | 2.4 (1.8) | 83 | 2.6 (1.9) | 0.525 | Gastric ulcer | 54 | 15% | 84 | 19% | 0.522 | Liver | 54 | 5% | 84 | 9% | 0.671 | Hypertension | 54 | 20% | 84 | 25% | 0.529 | Myocardial infarction | 54 | 13% | 84 | 13% | 0.982 | COPD | 54 | 13% | 84 | 13% | 0.982 | Arteriopathy | 54 | 11% | 82 | 15% | 0.553 | Connectivitis | 54 | 2% | 84 | 2% | 0.835 | Cancer | 54 | 24% | 84 | 19% | 0.053 | HIV | 54 | 0% | 84 | 0% | — | Diabetes (not complicated) | 56 | 9% | 86 | 7% | 0.671 | Diabetes (complicated) | 56 | 4% | 86 | 3% | 0.979 | Hematological | 54 | 7% | 84 | 4% | 0.316 |
| CHADS2 score | CHADS2 (points) | 56 | 2.3 (1.1) | 86 | 2.44 (1.3) | 0.557 | % CHADS2 ≥ 2 | 56 | 77% | 86 | 70% | 0.360 | Congestive | 54 | 28% | 84 | 37% | 0.267 | Hypertension | 54 | 67% | 84 | 55% | 0.165 | Age | 54 | 100% | 84 | 100% | — | Diabetes | 54 | 13% | 84 | 11% | 0.903 | Stroke | 54 | 15% | 84 | 23% | 0.284 |
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(c) ISAR (identification of senior at risk). |
| | Not anticoagulated | Anticoagulated | | | | % | | % |
| >3 drugs | 55 | 89% | 86 | 100% | 0.002 | Need of help before admission | 53 | 68% | 80 | 64% | 0.620 | Need for help | 53 | 45% | 80 | 40% | 0.546 | Visual disorders | 53 | 70% | 79 | 75% | 0.538 | Memory disorders | 52 | 50% | 80 | 42% | 0.398 | Hospitalized < 6 months | 52 | 33% | 83 | 52% | 0.030 |
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(d) Drugs |
| | Not anticoagulated | Anticoagulated | | | % | | % |
| Sintrom | 54 | 0% | 86 | 81% | 0.000 | LMWH | 54 | 0% | 86 | 19% | 0.001 | Antiaggregants | 54 | 43% | 86 | 20% | 0.004 | Digoxin | 54 | 7% | 86 | 20% | 0.003 | Blockers | 56 | 45% | 86 | 57% | 0.150 | Flecainide | 54 | 2% | 86 | 1% | 0.738 | Ca-antagonists | 54 | 20% | 86 | 16% | 0.230 | IEC | 54 | 35% | 86 | 34% | 0.723 | Amiodarone | 54 | 11% | 86 | 22% | 0.099 | ARB | 54 | 11% | 86 | 10% | 0.904 | NSAI | 54 | 2% | 86 | 2% | 0.851 |
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