HIV Infection in the Elderly: Arising Challenges

Table 2

Studies evaluating aging with HIV in sub-Saharan Africa.

Study, year	Aspect studied	Main findings
Negin and Cumming, 2010 [11]	Prevalence of HIV among elderly patients	Of the approximately 21 million people in sub-Saharan Africa aged ≥15 years that were HIV+, 14.3% were ≥50 years old
Negin et al., 2012 [115]	Prevalence of HIV and chronic comorbidities among those aged 50 years and older	Rates of chronic disease were higher among all older adults compared with those aged 18–49; of those aged 50 years and older, 29.6% had two or more of the seven chronic conditions compared with 8.8% of those aged 18–49 years
Greig et al., 2012 [118]	Associations between older age and adverse outcomes in HIV/AIDS antiretroviral programmes across 17 programmes in sub-Saharan Africa	Median gain in CD4 cell count at 6 and 12 months was significantly higher in patients less than 50 years old compared with those who are at least 50 years (134 versus 112 cells/μL at 6 months; 170 versus 139 cells/μL at 12 months; both < 0.001); in multivariate analysis, there was a significant increased risk of mortality beyond 3 months after ART initiation in all age groups of at least 40 years of age compared with less than 40 years