Journal of Biomedicine and Biotechnology
Volume 2008 (2008), Article ID 813236, 8 pages
doi:10.1155/2008/813236
Research Article
CD36 Is Significantly Correlated with Adipophilin in Human Carotid Lesions
and Inversely Correlated with Plasma ApoAI
Sophie Collot-Teixeira,
1,2 Calypso Barbatis,
3 Florence Bultelle,
2 Michael Koutouzis,
3 Gerard Pasterkamp,
4 Paul Fraser,
1 Zenon S. Kyriakides,
3 Robin N. Poston,
1 Angelique Ristagno,
2 Lilian McGregor,
5 Chantal M. Boulanger,
6 Guy Leseche,
7 and
John L. McGregor1,2,6
1Cardiovascular Division, King's College London, University of London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, UK
2Genomics and Atherothrombosis Laboratory, Thrombosis Research Institute, London SW3 6LR, UK
3Department of Pathology, Helenic Red Cross Hospital, Athens, Greece
4Laboratory of Experimental Cardiology, Utrecht University Hospital, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
5EA 3470/INSERM IFR63, Faculty of Medicine RTH Laennec, Claude Bernard-Lyon 1 University, 69372 Lyon Cedex 08, France
6INSERM U689, Centre de Recherche Cardiovasculaire, Hôpital Lariboisière, 75010 Paris, France
7Vascular Surgery Department, Bichat Hospital, 75018 Paris, France
Received 8 April 2008; Revised 18 June 2008; Accepted 29 July 2008
Academic Editor: Mohamed Boutjdir
Copyright © 2008 Sophie Collot-Teixeira et al. This is an open access article distributed under the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Linked References
- T. Doi, K.-I. Higashino, Y. Kurihara, et al., “Charged collagen structure mediates the recognition of negatively charged macromolecules by macrophage scavenger receptors,” The Journal of Biological Chemistry, vol. 268, no. 3, pp. 2126–2133, 1993.
- T. Mazzone, “Scavenger receptors in atherosclerosis: new answers, new questions,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 20, no. 12, pp. 2506–2508, 2000.
- V. V. Kunjathoor, M. Febbraio, E. A. Podrez, et al., “Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages,” The Journal of Biological Chemistry, vol. 277, no. 51, pp. 49982–49988, 2002. View at Publisher · View at Google Scholar · View at PubMed
- M. Febbraio, E. A. Podrez, J. D. Smith, et al., “Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice,” The Journal of Clinical Investigation, vol. 105, no. 8, pp. 1049–1056, 2000. View at Publisher · View at Google Scholar · View at PubMed
- E. Guy, S. Kuchibhotla, R. Silverstein, and M. Febbraio, “Continued inhibition of atherosclerotic lesion development in long term Western diet fed / mice,” Atherosclerosis, vol. 192, no. 1, pp. 123–130, 2007. View at Publisher · View at Google Scholar · View at PubMed
- K. J. Moore, V. V. Kunjathoor, S. L. Koehn, et al., “Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice,” The Journal of Clinical Investigation, vol. 115, no. 8, pp. 2192–2201, 2005. View at Publisher · View at Google Scholar · View at PubMed
- S. Collot-Teixeira, J. Martin, C. McDermott-Roe, R. Poston, and J. L. McGregor, “CD36 and macrophages in atherosclerosis,” Cardiovascular Research, vol. 75, no. 3, pp. 468–477, 2007. View at Publisher · View at Google Scholar · View at PubMed
- M. Febbraio and R. L. Silverstein, “CD36: implications in cardiovascular disease,” The International Journal of Biochemistry & Cell Biology, vol. 39, no. 11, pp. 2012–2030, 2007. View at Publisher · View at Google Scholar · View at PubMed
- S. M. Schwartz, Z. S. Galis, M. E. Rosenfeld, and E. Falk, “Plaque rupture in humans and mice,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 27, no. 4, pp. 705–713, 2007. View at Publisher · View at Google Scholar · View at PubMed
- Y. Nakagawa-Toyama, S. Yamashita, J.-I. Miyagawa, et al., “Localization of CD36 and scavenger receptor class A in human coronary arteries—a possible difference in the contribution of both receptors to plaque formation,” Atherosclerosis, vol. 156, no. 2, pp. 297–305, 2001. View at Publisher · View at Google Scholar
- C. Londos, D. L. Brasaemle, C. J. Schultz, J. P. Segrest, and A. R. Kimmel, “Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells,” Seminars in Cell & Developmental Biology, vol. 10, no. 1, pp. 51–58, 1999. View at Publisher · View at Google Scholar · View at PubMed
- G. Larigauderie, C. Furman, M. Jaye, et al., “Adipophilin enhances lipid accumulation and prevents lipid efflux from THP-1 macrophages: potential role in atherogenesis,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 24, no. 3, pp. 504–510, 2004. View at Publisher · View at Google Scholar · View at PubMed
- K. Nuotio, P. M. Isoviita, J. Saksi, et al., “Adipophilin expression is increased in symptomatic carotid atherosclerosis: correlation with red blood cells and cholesterol crystals,” Stroke, vol. 38, no. 6, pp. 1791–1798, 2007. View at Publisher · View at Google Scholar · View at PubMed
- X. Wang, T. J. Reape, X. Li, et al., “Induced expression of adipophilin mRNA in human macrophages stimulated with oxidized low-density lipoprotein and in atherosclerotic lesions,” FEBS Letters, vol. 462, no. 1-2, pp. 145–150, 1999. View at Publisher · View at Google Scholar
- P. J. Barter and K.-A. Rye, “The rationale for using apoA-I as a clinical marker of cardiovascular risk,” Journal of Internal Medicine, vol. 259, no. 5, pp. 447–454, 2006. View at Publisher · View at Google Scholar · View at PubMed
- H. C. Stary, A. B. Chandler, R. E. Dinsmore, et al., “A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association,” Circulation, vol. 92, no. 5, pp. 1355–1374, 1995.
- R. R. Johnson-Tidey, J. L. McGregor, P. R. Taylor, and R. N. Poston, “Increase in the adhesion molecule P-selectin in endothelium overlying atherosclerotic plaques. Coexpression with intercellular adhesion molecule-1,” The American Journal of Pathology, vol. 144, no. 5, pp. 952–961, 1994.
- R. N. Poston, D. O. Haskard, J. R. Coucher, N. P. Gall, and R. R. Johnson-Tidey, “Expression of intercellular adhesion molecule-1 in atherosclerotic plaques,” The American Journal of Pathology, vol. 140, no. 3, pp. 665–673, 1992.
- C. Albrecht, S. Soumian, J. S. Amey, et al., “ABCA1 expression in carotid atherosclerotic plaques,” Stroke, vol. 35, no. 12, pp. 2801–2806, 2004. View at Publisher · View at Google Scholar · View at PubMed
- A. Nakata, Y. Nakagawa, M. Nishida, et al., “CD36, a novel receptor for oxidized low-density lipoproteins, is highly expressed on lipid-laden macrophages in human atherosclerotic aorta,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 19, no. 5, pp. 1333–1339, 1999.