]>Effects of FR-91 on Immune Cells from Healthy Individuals and from Patients with Non-Hodgkin Lymphoma : Table 4
Table 4: Effect of FR-91 on production of cytokines by peripheral blood mononuclear cells from NHL patients.
IL-1 𝛽 controlIL-1 𝛽 /FR-91 10 microIL-1 𝛽 /FR-91 25 micro
X 2 . 5 2 ± 0 . 2 2 . 2 4 ± 0 . 4 5 2 . 2 1 ± 0 . 4 3
IL-2 controlIL-2/FR-91 10 microIL-2/FR-91 25 micro
X 4 . 6 7 ± 0 . 9 5 7 . 1 9 ± 2 . 5 8 ∗ 1 3 . 3 6 ± 5 . 9 8 ∗
IL-6 controlIL-6/FR-91 10 microIL-6/FR-91 25 micro
X 4 . 2 ± 0 . 9 6 6 . 8 9 ± 2 . 2 6 ∗ 1 4 . 1 3 ± 8 . 0 4 ∗
IL-8 controlIL-8/FR-91 10 microIL-8/FR-91 25 micro
X 2 . 1 6 ± 0 . 3 4 2 . 4 2 ± 0 . 2 4 2 . 2 1 ± 0 . 4 1
IL-10 controlIL-10/FR-91 10 microIL-10/FR-91 25 micro
X 2 . 1 8 ± 0 . 4 6 2 . 1 4 ± 0 . 4 8 2 . 1 4 ± 0 . 4 6
IL-12 controlIL-12/FR-91 10 microIL-12/FR-91 25 micro
X 4 . 6 8 ± 0 . 8 2 7 . 6 1 ± 2 . 5 ∗ 1 6 ± 7 . 3 6 ∗
IFN- 𝛾 controlIFN- 𝛾 /FR-91 10 microIFN- 𝛾 /FR-91 25 micro
X 3 . 8 6 ± 0 . 9 5 . 2 6 ± 2 . 0 2 ∗ ∗ 1 1 . 8 4 ± 6 . 1 2 ∗
TNF- 𝛼 controlTNF- 𝛼 /FR-91 10 microTNF- 𝛼 /FR-91 25 micro
X 4 . 8 6 ± 1 . 6 9 1 5 . 4 ± 8 . 4 ∗ 2 3 . 3 8 ± 7 . 8 3 ∗
X: mean ± SD; 𝑛 = 1 0 ; ∗ 𝑃 < . 0 0 5 ; ∗ ∗ 𝑃 < . 0 5 .