]>Tomatine Adjuvantation of Protective Immunity to a Major Pre-erythrocytic Vaccine Candidate of Malaria is Mediated via <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mtext>CD</mml:mtext><mml:msup><mml:mtext>8</mml:mtext><mml:mo>+</mml:mo></mml:msup></mml:mrow></mml:math> T Cell Release of IFN-<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mi>γ</mml:mi></mml:math> : Figure 1
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Figure 1: IFN- 𝛾 production by splenocytes from mice immunized with tomatine-P. berghei CS peptide following ex vivo restimulation with P. berghei CS peptide (25  𝜇 g/mL). Lymphocyte subset depletion was performed by immunomagnetic cell sorting to >98% purity. Data are fold increases in cytokine secretion over that of splenocytes from identically immunized mice not restimulated ex vivo (by convention, value = 1.0, depicted as a horizontal line). Data shown represent the mean of four mice, assayed individually in triplicate, from one of four similar experiments. ∗ 𝑃 < . 0 5 versus other groups, determined by the one-way ANOVA test.