Uncovering the Complexity of Transcriptomes with RNA-Seq
Figure 6
Alternative splicing. Schematic representation of the possible patterns of alternative splicing of a gene. Boxes are discrete exons that can be independently included or excluded from the mRNA transcript. Light blue boxes represent constitutive exons, violet and red boxes are alternatively spliced exons. Dashed lines represent alternative splicing events. (a) Canonical exon skipping; (b) 5 or (c) 3 alternative splicing; (d) Mutually exclusive splicing event involving the selection of only one from two or more exon variants; (e) Intra-exonic “cryptic” splice site causing the exclusion of a portion of the exon from the transcript; (f) Usage of new alternative 5 or (g) 3 exons; (h) Intron retention.
