Research Article

Structural Insights into Interaction between Mammalian Methionine Sulfoxide Reductase B1 and Thioredoxin

Figure 1

(a) Chemical shift difference observed for each residue of MsrB1 upon NMR titration by Trx. Lower panel shows in red the residues belonging to the protein active site revealing maximal changes upon titration. (b) The 3D structure of oxidized mammalian MsrB1. “Hot points” used for molecular docking are evidenced in red.
586539.fig.001a
(a)
586539.fig.001b
(b)