Posttranslational Modifications in Parasites and Their Role in Pathogenesis

Call for Papers

Posttranslational modifications (PTMs), the chemical modifications of a protein after its translation, can determine the protein activity state, localization, turnover, and interactions with other proteins. While PTMs are well characterized in mammalian and yeast cells, these processes have been less explored in parasites with the interest on these modifications being increased by the understanding of their role in parasite survival and pathogenesis. Also, knowledge and understanding of protozoa parasite PTMs might reveal unique aspects contributing to the understanding of eukaryotic adaptation and evolution.

We invite investigators to present original research articles as well as review articles that will enlighten the characteristic and implication of posttranslational modifications in parasites. Potential topics include, but are not limited to:

• Analysis of phosphorylation, acetylation, sumoylation, glycosylation, acylation, ubiquitination, polyGLY, polyGLU, PARylation, and protein degradation in parasites
• Latest methodologies for PTM evaluation applicable to parasites
• Role of PTM in cell signaling during parasites growth and differentiation
• PTM in parasites and protein structure
• Functional aspects of PTMs in parasite pathogenesis

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jbb/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:

Lead Guest Editor

• Maria Carolina Touz, Laboratory of Microbiology and Immunology, Instituto de Investigación Médica Mercedes y Martín Ferreyra (INIMEC-CONICET), CP5000 Córdoba, Argentina

Guest Editors

• Marco Lalle, Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanità, 00161 Rome, Italy
• Andrea Silvana Rópolo, Laboratory of Microbiology and Immunology, Instituto de Investigación Médica Mercedes y Martín Ferreyra (INIMEC-CONICET), CP5000 Córdoba, Argentina
• Thomas Naderer, Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia