Research Article

Association between a Tetranucleotide Repeat Polymorphism of SPAG16 Gene and Cataract in Male Children

Table 3

SHEsis predictions of frequencies of rs2289917-D2S2944 haplotypes in Indian pediatric cataract cases and control subjects.

Haplotype rs2289917-D2S2944Cases 2 (%)Controls 2 (%)Fisher’s P Odds ratio [CI95%]

C—<(GATA)1347 (33.6) 29 (45.3) 0.1116650.615 [0.337~1.122]
C—≥(GATA)1385 (60.7)22 (34.4) 0.0004532.952 [1.595~5.463]
T—<(GATA)1305 (03.6) 07 (10.9) 0.0389580.301 [0.091~0.996]
T—≥(GATA)13 03 (02.1) 06 (09.4) 0.0141890.200 [0.049~0.818]

Global is 17.23, df = 3, Fisher's P value is 0.000642.