Exploring the Membrane Mechanism of the Bioactive Peptaibol Ampullosporin A Using Lipid Monolayers and Supported Biomimetic Membranes

<table>Adsorption of AmpA at the air/water interface. (a) Adsorption isotherm (surface pressure <svg height="14.5" id="M16" style="vertical-align:-3.2316pt" version="1.1" viewbox="0 0 15.4375 14.5" width="15.4375" xmlns="http://www.w3.org/2000/svg">
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</svg> versus time) of AmpA at the air/water interface. AmpA was injected at a total concentration in the subphase of 250 nM. (b) Brewster angle microscopy images at the air/water interface recorded at the timepoints indicated by the numbered arrows in (a). GL: gray levels obtained with a shutter speed of 50 s<sup>−1</sup>. Arrows on photographs point to the peptide aggregates.</table>

Journal of Biophysics

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Figure 1

Figure 1: Exploring the Membrane Mechanism of the Bioactive Peptaibol Ampullosporin A Using Lipid Monolayers and Supported Biomimetic Membranes 