Research Article

pH-Dependent Interaction between C-Peptide and Phospholipid Bicelles

Figure 1

Secondary structure of C-peptide in LUVs at different pH as determined by CD. The figures depict CD spectra of 50  𝜇 M C-peptide in buffer (dotted line), in 1 mM POPC (continuous line), and in 1 mM POPC/POPG 1 : 1 (dashed line). (a) Shows spectra for C-peptide in 50 mM citrate buffer, pH 3.2, (b) for C-peptide in 50 mM sodium phosphate buffer, pH 5.8, and (c) for C-peptide in 50 mM sodium phosphate buffer, pH 6.9.
185907.fig.001a
(a)
185907.fig.001b
(b)
185907.fig.001c
(c)