Analysis of the REJ Module of Polycystin-1 Using Molecular Modeling and Force-Spectroscopy Techniques
Figure 3
Analysis of the mechanical stability of putative REJ domains 3 and 4. (a) Example of unfolding pattern observed after stretching the (I27)3-REJd4-(I27)2 protein. (b) Example of unfolding pattern observed after stretching the (I27)3-REJd3,4-(I27)2 protein. In these two examples the unfolding of the five titin I27 domains (they unfold on average at 200 pN with an increase length of 28 nm) is preceded by a long spacer.
