A New Proof of Concept in Bacterial Reduction: Antimicrobial Action of Violet-Blue Light (405 nm) in Ex Vivo Stored Plasma

Figure 3

405 nm light exposure of contaminated human plasma transfusion bags. (a) Three-dimensional model demonstrating the irradiance profile across the plasma bag, with irradiance of ~5 mWcm⁻² at the centre. (b) Inactivation of S. aureus contamination in 300 mL bags of human plasma by exposure to 405 nm light (n = 3 ± SE). Asterisks () represent data points, where the bacterial levels in light-exposed plasma were significantly different from the equivalent nonexposed control [].

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(b)