A New Proof of Concept in Bacterial Reduction: Antimicrobial Action of Violet-Blue Light (405 nm) in Ex Vivo Stored Plasma

Figure 4

Comparison of the exposure times (a) and doses (b) required for inactivation of S. aureus contamination in human plasma transfusion bags. (a) Inactivation kinetics was achieved utilising irradiance of 5, 16, and 48 mWcm⁻² at the centre of the bags. Results are presented as log₁₀ reduction (CFU mL⁻¹) as compared to the equivalent nonexposed control samples (n = 3 ± SD). Germicidal efficiency (GE) values for each irradiance are shown in (b). (GE is defined as log₁₀ reduction of a bacterial population by inactivation per unit dose in Jcm⁻²).

(a)

(b)