Research Article

Weight History, Smoking, Physical Activity and Breast Cancer Risk among French-Canadian Women Non-Carriers of More Frequent BRCA1/2 Mutations

Table 3

Odd ratios and 95% confidence intervals for breast cancer risk associated with lifestyle factors, including smoking and physical activity.

VariablesQ1Q2Q3 for trend

Smoking
Range (pack-years)≤0 >0 and ≤9.0 >9.0
Cases/Controls 106/13467/66107/80
Univariate OR (95% CI)1.001.28 ( )1.69 ( ).03
Multivariate (95% CI)1.35 ( )1.59 ( ).05
Moderate physical activity
Range (MET-hours/week)≤10.7>10.7 and ≤24.8>24.8
Cases/Controls80/10891/95109/77
Univariate OR (95% CI)1.000.68 ( )0.52 ( ).01
Multivariate (95% CI)0.67 ( )0.48 ( ).01
Vigorous physical activity
Range (MET-hours/week)≤0.11>0.11 and ≤7.2 >7.2
Cases/Controls91/9491/9298/94
Univariate OR (95% CI)1.001.02 ( )1.08 ( ).93
Multivariate (95% CI)1.01 ( )1.05 ( ).94
Total physical activity
Range (MET-hours/week)≤16.2> 6.2 and ≤33.2>33.2
Cases/Controls87/100 89/98 104/82
Univariate OR (95% CI)1.000.69 ( )0.72 ( ).14
Multivariate (95% CI) 0.57 ( )0.66 ( ).05

for age, education, physical activity, alcohol consumption, and total energy intake.
for age, education, alcohol consumption, smoking, and total energy intake.