Table 4: Stratified logistic regression models of smoking and adenoma occurrence among individuals undergoing screening colonoscopy in the New Hampshire colonscopy Registry from 2004–2006.

Adenoma v. No Adenoma
ModelOdds Ratio ( 9 5 % C l ) a

Full Model ( 𝑛 = 5 , 3 9 5 )
Smoking
 No pack-years1.00 (referent)
 15 pack-years or fewer1.07 (0.87–1.32)
 More than 15 pack-years1.54 ( 1 . 2 8 - 1 . 8 6 )
Sex
 Men1.00 (referent)
 Women 0 . 5 3 ( 0 . 4 5 - 0 . 6 2 )
F a m i l y H i s t o r y b
 Negative1.00 (referent)
 Positive 1 . 7 3 ( 1 . 4 0 - 2 . 1 5 )

Stratified by Sex

Male ( 𝑛 = 2 , 2 8 4 )
 No pack-years1.00 (referent)
 15 pack-years or fewer 1 . 3 2 ( 1 . 0 0 - 1 . 7 6 )
 More than 15 pack-years 1 . 5 5 ( 1 . 2 1 - 2 . 0 0 )
Female ( 𝑛 = 3 , 1 1 1 )
 No pack-years1.00 (referent)
 15 pack-years or fewer0.85 (0.61–1.14)
 More than 15 pack-years 1 . 5 5 ( 1 . 1 7 - 2 . 0 5 )

Stratified by Family History

Negative ( 𝑛 = 4 , 6 4 9 )
 No pack-years1.00 (referent)
 15 pack-years or fewer1.16 (0.92–1.46)
 More than 15 pack-years 1 . 5 6 ( 1 . 2 7 - 1 . 9 1 )
Positive ( 𝑛 = 7 4 6 )
 No pack-years1.00 (referent)
 15 pack-years or fewer0.77 (0.4 7–1.26)
 More than 15 pack-years1.50 (0.94–2.38)

a O d d s ratios are adjusted for age in all models, and for family history in the sex-stratified models, and for sex in the family history-stratified models. b F a m i l y history was defined as a reported diagnosis of colon or rectal cancer in a mother, father, sibling, or child of the patient.
𝑃 = . 0 5 .
𝑃 . 0 0 1 .