Risk of Late Mortality and Second Malignant Neoplasms among 5-Year Survivors of Young Adult Cancer: A Report of the Childhood, Adolescent, and Young Adult Cancer Survivors Research Program
Table 1
Characteristics of young adult cancer survivors by sex.
Characteristic
Entire cohort N (%)
Male N (%)
Female N (%)
Overall
1248
589 (47.2)
659 (52.8)
Type of original cancer
Lymphoma
307 (24.6)
162 (27.5)
145 (22)
Central nervous system tumor
59 (4.7)
36 (6.1)
23 (3.5)
Soft tissue sarcoma
66 (5.3)
40 (6.8)
26 (4.0)
Germ cell tumor
178 (14.3)
161 (27.3)
17 (2.6)
Melanoma
222 (17.8)
80 (13.6)
142 (21.5)
Carcinoma
341 (27.3)
71 (12.1)
270 (41)
Othersa
75 (6.0)
39 (6.6)
36 (5.5)
Birth year
1945–1954
271 (21.7)
115 (19.5)
156 (23.7)
1955–1964
528 (42.3)
261 (44.3)
267 (40.5)
1965–1975
449 (36)
213 (36.2)
236 (35.8)
Diagnosis period
1970–1979
394 (31.6)
170 (28.9)
224 (34.0)
1980–1989
520 (41.7)
259 (44)
261 (39.6)
1990–1995
334 (26.8)
160 (27.2)
174 (26.4)
Attained age (years)
25–39
366 (29.3)
179 (30.4)
187 (28.4)
40–49
522 (41.8)
265 (45)
257 (39.0)
50+
360 (28.8)
145 (24.6)
215 (32.6)
Follow-up time (years)
5–19 years
521 (41.7)
250 (42.4)
256 (38.8)
20+ years
727 (58.3)
339 (57.6)
403 (61.2)
Relapse < 5 years after diagnosis
Yes
82 (6.6)
46 (7.8)
36 (5.5)
No
1166 (93.4)
543 (92.2)
623 (94.5)
Vital status
Dead
138 (11.1)
84 (14.3)
54 (8.2)
Alive
1110 (88.9)
505 (85.7)
605 (91.8)
SMN 5 years after diagnosis
Yes
62 (5)
25 (4.2)
37 (5.6)
No
1186 (95)
564 (95.8)
622 (94.4)
Having chemotherapy
Yes
342 (27.4)
200 (34)
142 (21.5)
No
552 (44.2)
267 (45.3)
285 (43.2)
Missing
354 (28.4)
122 (20.7)
232 (35.2)
Having radiation
Yes
369 (29.6)
204 (34.6)
165 (25.0)
No
879 (70.4)
385 (65.4)
494 (75.0)
Having surgery
Yes
628 (50.3)
332 (56.4)
296 (44.9)
No
270 (21.6)
137 (23.3)
133 (20.2)
Missing
350 (28.0)
120 (20.4)
230 (34.9)
aOther types of original cancers include leukemia, bone tumor, and miscellaneous-specified tumor.
